PIPERINE-LOADED CHITOSAN NANOPARTICLES: PREPARATION AND CHARACTERIZATION

Authors

  • Tran Thi Y Nhi Institute of Chemistry -VAST
  • Cong Duc Trinh Lab of Natural Polymer
  • Thien Do Truong Lab of Natural Polymer, Institute of Chemistry, VAST
  • Tuan Le Quang Lab of Natural Polymer, Institute of Chemistry, VAST
  • Hanh Bich Pham Lab of Natural Polymer, Institute of Chemistry, VAST
  • Thuy Thi Lai Lab of Natural Polymer, Institute of Chemistry, VAST
  • Ha Thi Thanh Le Lab of Natural Polymer, Institute of Chemistry, VAST

DOI:

https://doi.org/10.15625/2525-2518/59/4/15523

Keywords:

piperine, chitosan, nanoparticles

Abstract

  1. Abstract – HCTN7. Plasma cholesterol level plays an important role in atherosclerosis and cardiovascular diseases. Piperine, an alkaloid form of black pepper is known to reduce cholesterol uptake. In this paper, piperine-loaded chitosan nanoparticles (CTS-PIP NPs) were prepared by ionic gelation method. Molecular interactions among the components were confirmed by FT-IR spectroscopy. Transmission electron microscopy (TEM) images revealed spherical-shaped nanoparticles with diameter of <100 nm. CTS-PIP NPs displayed positive ζ-potential(ZP) of about 31.6 mV. Dynamic light scattering (DLS) particle size (PS) distribution analysis indicated the mean particle size of CTS-PIP NPs was 245.9 nm, polydispersity index of 31%

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Author Biography

Tran Thi Y Nhi, Institute of Chemistry -VAST

Lab of Natural Polymer

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Published

2021-08-13

How to Cite

Nhi, T. T. Y., Trinh, C. D., Truong, T. D., Quang, T. L., Pham, H. B., Lai, T. T., & Le, H. T. T. (2021). PIPERINE-LOADED CHITOSAN NANOPARTICLES: PREPARATION AND CHARACTERIZATION. Vietnam Journal of Science and Technology, 59(4), 480. https://doi.org/10.15625/2525-2518/59/4/15523

Issue

Section

Natural Products