Hợp chất lignan glycosid mới từ cây bù dẻ râu Uvaria fauveliana


Authors

  • Hồ Việt Đức
  • Nguyễn Thị Hoài
  • Đỗ Thị Thảo
  • Bùi Hữu Tài
  • Châu Văn Minh
  • Phan Văn Kiệm
DOI: https://doi.org/10.15625/0866-7144.2014-0013

Keywords:

Uvaria fauveliana, lignan glycoside, cytotoxicity

Abstract

Chemical investigation of the aerial parts of Uvaria fauveliana yielded one new lignan glycoside, (8S,8’S)-4,4’-dihydroxy-3,5,3’,5’-tetramethoxy-8,8’-butyrolignan 9-O-α-L-rhamnopyranoside (1), along with two known compounds, oxoanolobine (2) and ergosta-4,6,8(14),22-tetraen-3-one (3). Their chemical structures were established by NMR, HR-MS analysis and in comparison with the reported data. Compounds 2 and 3 displayed moderate cytotoxicity against human lung adenocarcinoma cancer cell line (LU-1) with IC50 values of 9.22±1.02, 10.21±1.16 μg/mL, respectively.

Keywords: Uvaria fauveliana, lignan glycoside, cytotoxicity.

Downloads

Download data is not yet available.

Downloads

Abstract View: 219
PDF Downloaded: 33

Published

17-09-2014

How to Cite

Đức, H. V., Hoài, N. T., Thảo, Đỗ T., Tài, B. H., Minh, C. V., & Kiệm, P. V. (2014). Hợp chất lignan glycosid mới từ cây bù dẻ râu Uvaria fauveliana. Vietnam Journal of Chemistry, 52(4), 463. https://doi.org/10.15625/0866-7144.2014-0013

Issue

Vol. 52 No. 4 (2014)

Section

Articles