A practical synthesis of fluoroquinolone antibiotic moxifloxacin


Authors

  • Le Nguyen Thanh Nhà xuất bản Khoa học Tự nhiên và Công nghệ
  • Tran Huu Giap
  • To Hai Tung
  • Nguyen Anh Dung
  • Van Thi My Hue
  • Cao Thi Hue
  • Nguyen Thi Minh Hang
  • Nguyen Van Hung
  • Chau Van Minh
DOI: https://doi.org/10.15625/0866-7144.2015-2e-012

Keywords:

Fluoroquinolone, antibiotic, moxifloxacin

Abstract

The fluoroquinoloneantibiotic has been used in clinical practice since the 1980s, primarily for the treatment infections caused by Gram-negative bacteria. Moxifloxacin, a fourth-generation fluoroquinolone antibiotic developed by pharmaceutical company Bayer AG, exhibit broad spectrum of activity against Gram-negative, Gram-positive bacteria as well as  anaerobia. Moxifloxacin is used for community-acquired respiratory tract infections, sinusitis, acute exacerbations of chronic bronchitis and pneumonia, and skin structure infections. We have described the synthesis of moxifloxacin using difluoroboron complex. In this paper, a practical synthesis of moxifloxacin using acetoxyboronate complexwas reported.

Downloads

Download data is not yet available.

Downloads

Abstract View: 200
PDF Downloaded: 310

Published

21-05-2015

How to Cite

Thanh, L. N., Giap, T. H., Tung, T. H., Dung, N. A., My Hue, V. T., Hue, C. T., Minh Hang, N. T., Hung, N. V., & Minh, C. V. (2015). A practical synthesis of fluoroquinolone antibiotic moxifloxacin. Vietnam Journal of Chemistry, 53(2e), 52–55. https://doi.org/10.15625/0866-7144.2015-2e-012

Issue

Vol. 53 No. 2e (2015)

Section

Articles