Tổng hợp một số 2-amino-6-aryl-4-(4’-hydroxy-n-metylquinolin-2’-on-3’-yl)pyrimidin


Authors

  • Dương Ngọc Toàn
  • Trần Phương Anh
  • Nguyễn Minh Thảo
DOI: https://doi.org/10.15625/2525-2321.2017-00460

Keywords:

Pyrimidines, methylquinolin, guanidine chlorohydrate, a, b-unsaturated ketones.

Abstract

Six new 2-amino-6-aryl-4-(4’-hydroxy-N-methylquinolin-2’-on-3’-yl)pyrimidines have been synthesized from a,b-unsaturated ketones of 3-acetyl-4-hydroxy-N-methylquinolin-2-on by reaction of corresponding a,b-unsaturated ketones with guanidine chlorohydrate. The purity and structure of the obtained products have been confirmed by thin layer chromatography, IR, 1H NMR, 13C NMR, HSQC, HMBC and MS spectra.

Keywords. Pyrimidines, methylquinolin, guanidine chlorohydrate, a,b-unsaturated ketones.

References

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Published

30-06-2017

How to Cite

Toàn, D. N., Anh, T. P., & Thảo, N. M. (2017). Tổng hợp một số 2-amino-6-aryl-4-(4’-hydroxy-n-metylquinolin-2’-on-3’-yl)pyrimidin. Vietnam Journal of Chemistry, 55(3), 290. https://doi.org/10.15625/2525-2321.2017-00460

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Articles