Synthesis and cytotoxicity of some acetylated alkaloids of Hymenocallis littoralis


Authors

  • Dinh Thi Phuong Anh
  • Tran Bach Duong
  • Vu Dinh Hoang
DOI: https://doi.org/10.15625/4871

Keywords:

Hymenocallis littoralis, alkaloid, acetylated derivatives, cytotoxicity activity.

Abstract

11-O-acetyltazettine (2), 2-O-acetyllycorine (4), 1,2-O,O’-diacetyllycorine (5), and 11-O-acetylhaemanthamine (7) were synthesized  from tazettine (1), lycorine (3) and haemanthamine (6) isolated from the whole plant of Hymenocallis littoralis. Structures of the compounds were elucidated by means of spectroscopic methods. All the alkaloids and their derivatives were tested for cytotoxicity activities to KB and Hep G2 cell lines.

Keywords: Hymenocallis littoralis, alkaloid, acetylated derivatives, cytotoxicity activity.

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Published

10-09-2014

How to Cite

Phuong Anh, D. T., Duong, T. B., & Hoang, V. D. (2014). Synthesis and cytotoxicity of some acetylated alkaloids of Hymenocallis littoralis. Vietnam Journal of Chemistry, 52(2), 152. https://doi.org/10.15625/4871

Issue

Vol. 52 No. 2 (2014)

Section

Articles